How Do Brains Develop? Insights into Neurological Development from Electron Microscopy Data
Electron microscopy has created the first nanoscale maps of brains, and APL has developed the largest database of such datasets for the US BRAIN Initiative. This effort utilizes a unique dataset of 9 worms, imaged at different timepoints in life, to provide the first nanoscale insight into brain development. Building on previous work, we analyze patterns in changes in neurons and synapses over development, which will lay the groundwork for future work on mammalian brains.